Alzheimer’s disease (AD) is the most common form of dementia among older people. Dementia is a brain disorder that seriously affects a person’s ability to carry out daily activities. AD begins slowly. It first involves the parts of the brain that control thought, memory and language.
Recent years have brought a wealth of new scientific understanding regarding how medical marijuana cannabis can be beneficial for treating Alzheimer’s.
A related problem, mild cognitive impairment (MCI), causes more memory problems than normal for people of the same age. Many, but not all, people with MCI will develop AD.In AD, over time, symptoms get worse. People may not recognize family members or have trouble speaking, reading or writing. They may forget how to brush their teeth or comb their hair. Later on, they may become anxious or aggressive, or wander away from home. Eventually, they need total care. This can cause great stress for family members who must care for them.
Medical Marijuana Efficiency
A pre-clinical study published in the Journal of Alzheimer’s Disease, have suggested that very small doses of THC, one of the chemical found in marijuana, slow down the production of the beta-amyloid protein, which over time builds up to create plaques in the brain, an accumulation of which is a known hallmark of Alzheimer’s disease.
Similar studies have also shown the effectiveness of THC in fighting the formation of harmful brain plaques. Researchers in a 2006 study conducted by the Scripps Institute found that medical marijuana was even better than the best known inhibitors, found in existing Alzheimer’s drugs and the THC blocked the aggregation of plaques completely.
Alzheimer’s and Cannabis (Marijuana) Related Clinical Information
- A Molecular Link Between the Active Component of Marijuana and Alzheimer’s Disease Pathology
- Article: Marijuana may help stave off Alzheimer’s
- Marijuana’s Active Ingredient Shown to Inhibit Primary Marker of Alzheimer’s Disease
- Cannabinol Delays Symptom Onset
- Cannabis Relieves Lou Gehrigs Symptoms
- ‘Medical’ Marijuana: 10 Health Benefits That Legitimize Legalization
- NORML – Alzheimer’s Disease
Official Research Reports
- The activation of cannabinoid CB2 receptors stimulates in situ and in vitro beta-amyloid removal by human macrophages.
- Cannabinoids as Therapeutic Agents for Ablating Neuroinflammatory Disease
- The Cannabinoid Receptor agonist Nabilone for the Treatment of Dementia-related Agitation.
- Alzheimer’s disease; taking the edge off with cannabinoids?
- Delta-9-tetrahydrocannabinol for night-time agitation in severe dementia.
- Prevention of Alzheimer’s Disease Pathology by Cannabinoids: Neuroprotection Mediated by Blockade of Microglial Activation
- Open-label study of dronabinol in the treatment of refractory agitation in Alzheimer’s disease: a pilot study